projectchris

Boards Post

projectchris posted to the Spectrum Pharmaceuticals, Inc. board. 10:31 PM

4th quarter 2012

http://seekingalpha.com/article/1213261-spectrum-pharmaceuti...


We had record [more]

Boards Post

projectchris replied to the Health Care Reform board. 11:19 PM

Re: First look at Obamacare health ins. premiums

Gee, I could have sworn that MA has the Romneycare model.

Is there really much difference?

Boards Post

projectchris replied to the Health Care Reform board. 7:18 PM

Re: First look at Obamacare health ins. premiums

Those states would be Ma, NJ, NY, RI, & SURPRISE VT.

I would add that these states have the highest monthly premiums in the nation already. We already know Massachusetts already has the Obamacare model, and wouldn't you know it [more]

Boards Post

projectchris replied to the Exelixis, Inc. board. 7:31 PM

Re: Blast from Past

Could it be that EXEL was "played" on abandoning viable drugs due to "toxicity" that for some reason no longer prohibits these same drugs from becoming blockbusters????

Ah, bringing back old memories of the [more]

Boards Post

projectchris replied to the Exelixis, Inc. board. 11:34 AM

Re: Cabo + Abiraterone late breaker

"AR drugs are thought to develop resistance through MET, and blocking both at the same time may demonstrate a sum larger than parts, analagy sort of speak. I think we could see tumor shrinkage above what Abiraterone alone would [more]

Boards Post

projectchris replied to the Exelixis, Inc. board. 10:42 AM

Re: Cabo + Abiraterone late breaker

This drug BTW......did have activity measurable by PSA......unlike Cabo?

not quite entirely true. Cabo certainly had discordant effects relative speaking on PSA, but some had lowered PSA, some elevated, and some plateau. This may be [more]

Boards Post

projectchris replied to the Exelixis, Inc. board. 10:19 AM

Re: Cabo + Abiraterone late breaker

I don't think it's pre-chemo.

"CRPC with up to 2 prior chemotherapy regimens"

This link describes some of the rationale for the trial:

[more]

Boards Post

projectchris replied to the Exelixis, Inc. board. 10:12 AM

Re: Cabo + Abiraterone late breaker

This is phase 1 so probably 5+ years away from any revenues, but positive results specially for PFS and OS will move the stock price, methinks?

I really didn't address this question to what you were asking. I would have to look at the [more]

Boards Post

projectchris replied to the Exelixis, Inc. board. 9:56 AM

Re: Cabo + Abiraterone late breaker

Prechemo!! does that mean this is first line prostrate cancer instead of the 3rd line that the current trials are in progres for?

per exelixis recent presentations- Exelixis is planning a randomized phase 2 combination with hormonal [more]

Boards Post

projectchris posted to the Exelixis, Inc. board. 6:23 PM

Cabo + Abiraterone late breaker

[more]

Boards Post

projectchris replied to the Exelixis, Inc. board. 6:28 PM

Re: Cabo and Tivantinib in HCC

I wonder if Cabo would recruit faster without biopsy inclusion criteria?

I probably stated this in way to confuse, so I will add a little context.

Exelixis stated at ASCO that IHC MET determinaton was hard to collect. From [more]

Boards Post

projectchris posted to the Exelixis, Inc. board. 6:11 PM

Cabo and Tivantinib in HCC

Interesting observation by Biobetter on Investor Village.

[more]

Boards Post

projectchris replied to the Exelixis, Inc. board. 5:50 PM

Re: EXEL clearly missed !

Osteolytic lesions typically are not demonstrated by bone scan.


I probably overstated this, and checked some literature to be more certain. Here is a link that suggests 50% of lytic lesions in multiple myeloma are visualized by [more]

Boards Post

projectchris replied to the Exelixis, Inc. board. 9:46 PM

Re: EXEL clearly missed !

There has been some chatter regarding off label use and insurance reimbursing for it on the Yahoo! boards.

My opinion hasn't changed, I just don't see significant off label sales here. Interesting anecdotal evidence, again with that [more]

Boards Post

projectchris replied to the Tax Strategies board. 8:34 PM

Re: Dividend not included on 1099 form

"Since you indicate that the dividend was received on January 3 I would be inclined to think is was actually issued the prior year.
You could check with a quote server such as Yahoo Finance that shows dividend dates to see when it was [more]

Boards Post

projectchris replied to the Tax Strategies board. 11:35 PM

Re: Dividend not included on 1099 form

Are you sure the dividend wasn't taxable in 2011? Some dividends received in January are taxable in the previous tax year.

I looked at my 1099-DIV from 2011 tax year, and it wasn't reported on that form either. I received the one time [more]

Boards Post

projectchris posted to the Tax Strategies board. 9:45 PM

Dividend not included on 1099 form

I have a dividend that I collected in January 2012 that was not included on my 1099-DIV form. I finally got the 1099 form as Tradeking uses Apex Clearing. Tradeking/Zecco is again having problems with 1099 forms, and I finally received mine today. A [more]

Boards Post

projectchris posted to the Health Care Reform board. 5:24 PM

Welch and Buffett Agree on obamacare

Welch and Buffett Agree: Obamacare Slows Down the Economy

I appreciate Buffett's honesty, too many try to pretend obamacare will not accelerate health care costs or somehow try to give the impression costs will go down.


[more]